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1. Leukotriene receptor antagonists

   Leukotriene receptor antagonists (LTRAs) block the action of leukotriene D4 (and to a lesser extent leukotrienes C₄ and E₄) on the cysteinyl leukotriene receptor CysLT₁ in the lungs and bronchial tubes. This action reduces the inflammatory bronchoconstriction caused by leukotriene. LTRAs are not suitable for treating acute asthma attacks. They do not interact with theophyllines, as they operate by different molecular mechanisms.

   smaxwell - 10/10/2014 - 7:43pm

2. Asthma

   Asthma affects 300 million people worldwide and is characterized by respiratory symptoms that burden patients and can lead to exacerbations which require medical attention and can be fatal. Common symptoms of asthma include wheezing, chest tightness, cough and shortness of breath. These symptoms are caused by inflammation and hyperreactivity in the airways leading to bronchoconstriction or airway narrowing. There are many triggers for patients with asthma including dust and allergens, pollution, cigarette smoke and even exercise or stress.

   efaccena - 11/03/2019 - 10:52am