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1. Kinase inhibitors

   Protein and (lipid kinases) represent an important target class for treating human disorders, as their aberrant activity underlies a variety of pathologies, ranging from cancer, inflammatory diseases, diabetes, infectious diseases, and cardiovascular disorders.

   efaccena - 08/03/2016 - 1:38pm

2. Drug metabolizing enzymes

   Cytochrome P450 enzymes are the main drug metabolising enzymes (xenobiotic inactivators) in humans, and these are the primary contributors to Phase I oxidative metabolism of drugs and other chemicals.

   efaccena - 08/03/2016 - 9:21am