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1. Intravenous general anaesthetics

   Propofol is the most widely used intravenous anaesthetic. It can be used for induction or maintenance of anaesthesia.

   Thiopental sodium is used for induction, but has no analgesic action. As metabolism is slow repeated doses have a cumulative effect and recovery is much slower.

   efaccena - 31/05/2017 - 2:34pm

2. Drug metabolizing enzymes

   Cytochrome P450 enzymes are the main drug metabolising enzymes (xenobiotic inactivators) in humans, and these are the primary contributors to Phase I oxidative metabolism of drugs and other chemicals.

   efaccena - 08/03/2016 - 9:21am