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Antihistamines (under construction)
The antihistamines recommended for or prescribed to treat allergic reactions, occasional insomnia, motion sickness or vertigo, and nausea and vomiting target histamine H1 receptors on mast cells, smooth muscle, endothelium, and in the brain’s tuberomammillary nucleus (a structure of histamine-releasing neurons in the posterior third of the hypothalamus involved in regulating arousal, learning, memory, sleep and energy balance). Antihistamine drugs act mechanistically as receptor antagonists or inverse agonists.
efaccena - 09/09/2016 - 9:21am
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Hypnotic and anxiolytic drugs
The pharmacology of drugs with anxiolytic, sedative, and hypnotic effects overlaps significantly, with different doses of the same drug having effects ranging from sedation to loss of consciousness. So it can be difficult to ascribe just one function to each drug. The job of the prescriber is to identify the drug which offers the best therapeutic outcome for their patient.
smaxwell - 10/10/2014 - 7:53pm