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  1. Antipsychotic drugs

    Antipsychotic use is associated with significant side-effects, most notably movement disorders (tardive dyskinesia) and weight gain. It is unclear whether the atypical (second-generation) antipsychotics offer advantages over older, first generation antipsychotics. Drop-out and symptom relapse rates are similar for both classes of drugs.

    Both generations of medication block receptors in the brain's dopamine pathways, but atypical antipsychotics often act on serotonin receptors as well.

    smaxwell - 10/10/2014 - 7:56pm

  2. Schizophrenia

    Schizophrenia is a chronic brain disorder characterised by hallucinations, delusions, formal thought and movement disorders, behavioural changes and a lack of motivation. Symptoms are traditionally divided into positive and negative. The diagnosis is made clinically after a full psychiatric history and other causes of psychosis are excluded. The pathophysiology and causes of schizophrenia are multifaceted and extremely complex and there is no full understanding why it occurs. It has a relatively low prevalence affecting less than 1% of people in their lives.

    efaccena - 05/06/2023 - 9:46am

  3. Mood stabilising drugs

    A variety of chemotypes are grouped together as the mood stabilising drugs, used in the management of bipolar disorder (manic depression), mania and hypomania, and sometimes recurrent severe depression. Naming these drugs as mood stabilisers belies their action of stabilising mood in patients who experience problems with extreme highs, extreme lows, or mood swings between extreme highs and lows.

    Mood stabilisers should only be prescribed by mental health professionals, such as psychiatrists.

    smaxwell - 10/10/2014 - 7:56pm