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1. Other antianginal drugs

   Stable angina usually results from atherosclerotic plaques in the coronary arteries. This restricts blood flow and oxygen supply to the heart. Stable angina is often precipitated by exertion and relieved by rest.

   Stable angina medications include nitrates (the drugs of choice), calcium-channel blockers (CCBs), beta-blockers and potassium channel activators. These drug families have vasodilatory effects which reduce blood pressure. Arteriolar dilatation reduces peripheral vascular resistance and left ventricular pressure during systole resulting in improved cardiac output.

   smaxwell - 10/10/2014 - 9:10am

2. Antiarrhythmic drugs (made easy)

   This 23-min video describes the classification and effects of antiarrhythmic drugs starting at about 12 min from the beginning. Before that, basic electrophysiology of the heart and mechanisms of arrhythmias are described. This video is created by Speed Pharmacology.

   efaccena - 15/03/2022 - 2:16pm

3. Heart failure

   Heart failure (HF) is caused by the heart’s inability to pump enough blood to meet the body’s needs. In response, the body activates compensatory mechanisms, such as the sympathetic nervous system which leads to tachycardia, sodium and water retention, vasoconstriction, and over time, ventricular hypertrophy, all geared towards increasing cardiac output. Leading causes of HF are coronary artery disease and hypertension.

   efaccena - 11/03/2019 - 11:56am