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Nitrates
Nitrate medicines include glyceryl trinitrate (GTN), isosorbide dinitrate and isosorbide mononitrate, prescribed under a number of trade names. Nitrates cause vasodilation by activating soluble guanylyl cyclase.
Used to treat the symptoms, not the underlying cause, of angina.
smaxwell - 10/10/2014 - 9:08am
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Heart failure
Heart failure (HF) is caused by the heart’s inability to pump enough blood to meet the body’s needs. In response, the body activates compensatory mechanisms, such as the sympathetic nervous system which leads to tachycardia, sodium and water retention, vasoconstriction, and over time, ventricular hypertrophy, all geared towards increasing cardiac output. Leading causes of HF are coronary artery disease and hypertension.
efaccena - 11/03/2019 - 11:56am