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  1. Inhalational general anaesthetics

    Inhalational anaesthetics include gases and volatile liquids.


    Volatile liquid anaesthetics

    Isoflurane is the preferred inhalational anaesthetic for use in obstetrics. It causes muscle relaxation in its own right and potentiates the effects of muscle relaxant drugs.

    efaccena - 31/05/2017 - 2:54pm

  2. Ligand-gated ion channels

    Ligand-gated ion channels (LGICs) mediate passive ion flux driven by the electrochemical gradient for the permeant ions. LGICs are gated by the binding of a specific ligand to an orthosteric site(s) that triggers a conformational change that results in the conducting state, or by binding of endogenous, or exogenous, modulators to allosteric sites. LGICs are responsible for fast synaptic transmission in the nervous system and at the somatic neuromuscular junction.

    efaccena - 24/02/2016 - 3:56pm