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Venous thromboembolism
Venous thromboembolism (VTE) is a blood clot in a vein. VTEs can partially or completely obstruct blood flow. The most frequent types of VTE are
- deep-vein thrombosis (DVT) and
- pulmonary embolism (PE)
Pharmacological VTE prophylaxis and treatment relies on the use of different classes of drugs; anti-coagulants, antiplatelet drugs and thrombolytic/fibrinolytic agents.
efaccena - 18/04/2023 - 2:18pm
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Anticoagulant drugs
Anticoagulants are used to prevent the formation or growth of fibrin/erythrocyte thrombi in the venous circulation. They are not useful for treating arterial thrombi which are mainly composed of platelet aggregates.
Anticoagulants can be administered parenterally or orally.
smaxwell - 10/10/2014 - 9:11am
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Ischemic heart disease
Oxygen demand of the heart dynamically changes, and the coronary artery can adjust its blood flow to fulfill the myocardial oxygen demand (coronary blood flow reserve). Normally, the oxygen supply and the oxygen demand are well balanced in healthy subjects. When the oxygen supply to the heart becomes inadequate for the needs of the heart, myocardial ischemia occurs. That is, ischemic heart disease (IHD) is caused by an imbalance between the oxygen supply (coronary blood flow) and the oxygen demand of the heart.
efaccena - 13/02/2018 - 10:14am