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  1. NSAIDs (inflammation)

    NSAIDs have historically been classified according to their chemical composition, but as mechanism of action has come to the fore, this is also used to classify these drugs.

    NSAIDs within classes have similar characteristics and tolerability, with little difference in clinical efficacy at equivalent doses. The prescribers’ choice will be determined by other factors such as dosing regimens, route of administration and tolerability. For example, ibuprofen and diclofenac have half-lives of just 2–3 hours, whereas the oxicams have half-lives 10 times longer.

    efaccena - 09/09/2016 - 9:27am

  2. Cyclooxygenase (COX) inhibitors

    Cyclooxygenase (COX) inhibitors are non-steroidal anti-inflammatory drugs (NSAIDs), used clinically to relieve fever and pain, such as those associated with headaches, colds, flu, and arthritis. NSAIDs are available by prescription and over-the-counter (OTC).

    efaccena - 08/03/2016 - 9:19am

  3. Transporters as drug targets, and drug interactions

    Monoamine reuptake transporters

    efaccena - 21/03/2016 - 1:57pm

  4. NSAIDs for musculoskeletal conditions

    There are about 20 different nonsteroidal anti-inflammatory drugs (NSAIDs) available. Some, such as aspirin and ibuprofen, are widely available over-the-counter (OTC). Others are only available on prescription. NSAIDs are the most frequently used medicines for symptomatic relief in osteoarthritis (OA), the most common form of arthritis, and are often prescribed to rheumatoid arthritis (RA) patients.

    efaccena - 22/07/2016 - 8:25am