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  1. Drugs for SARS-CoV-2 infection (COVID-19)

    COVID-19 is the disease caused by infection by SARS-CoV-2 (severe acute respiratory syndrome virus 2), the airbourne, respiratory coronavirus that was first detected in China’s city of Wuhan in late 2019. The spread of this virus rapidly became a global pandemic that has resulted in millions of deaths. The pace of the subsequent response by the medical, pharmacology, scientific and pharmaceutical research communities has been unprecedented and delvered significant advances in both vaccinations and therapeutic interventions.

    efaccena - 05/04/2022 - 11:39am

  2. Corticosteroids

    The anti-inflammatory corticosteroids act as glucocorticoid receptor agonists and modulate expression of genes containing the glucocorticoid response element (GRE).

    efaccena - 09/09/2016 - 9:44am

  3. Anti-emetic drugs

    Drug-induced emesis can now be largely controlled with anti-emetic drugs, however, nausea remains a very significant clinical problem. This dichotomy suggests that different mechanisms underlie nausea and vomiting.

    smaxwell - 10/10/2014 - 7:50pm

  4. Mitotic spindle poisons

    Mechanism of action

    efaccena - 30/03/2023 - 2:01pm

  5. Drugs for hyperthyroidism

    Thioamides, such as carbimazole and propylthiouracil, inhibit thyroid peroxidase and interfere with the formation of thyroid hormones. Carbimazole is a prodrug metabolised to the active metabolite thiamazole (also known as methimazole).

    efaccena - 02/12/2022 - 12:07pm