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  1. Inhalational general anaesthetics

    Inhalational anaesthetics include gases and volatile liquids.


    Volatile liquid anaesthetics

    Isoflurane is the preferred inhalational anaesthetic for use in obstetrics. It causes muscle relaxation in its own right and potentiates the effects of muscle relaxant drugs.

    efaccena - 31/05/2017 - 2:54pm

  2. Muscle relaxants

    Muscle relaxants are a group drugs that act as central nervous system depressants which have overall sedative and musculoskeletal relaxant properties. Examples from many different drug classes have these effects, despite their different mechanisms of action. Muscle relaxants should preferably be prescribed short-term to reduce skeletal muscle spasms, provide relief from pain, and increase mobility of the affected muscles and should where appropriate be used together with rest and physical therapy as part of an overall recovery strategy.

    efaccena - 22/07/2016 - 8:28am

  3. General anaesthetics

    General anaesthetics (GAs) cause a controlled and reversible loss of consciousness, analgesia and amnesia, but despite having been in use for over 150 years, the precise mechanism of action of commonplace GAs is still not fully understood. A variety of compounds with widely different chemical structures can act as GAs. Central nervous system (CNS) areas affected by GAs include the cerebral cortex, thalamus, reticular activating system and spinal cord, and potential molecular targets include GABA, NMDA, serotonin (5-HT) and glycine receptors, as well as voltage-gated ion channels.

    efaccena - 31/05/2017 - 10:54am