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Transporters as drug targets, and drug interactions
Monoamine reuptake transporters
efaccena - 21/03/2016 - 1:57pm
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Drug metabolizing enzymes
Cytochrome P450 enzymes are the main drug metabolising enzymes (xenobiotic inactivators) in humans, and these are the primary contributors to Phase I oxidative metabolism of drugs and other chemicals.
efaccena - 08/03/2016 - 9:21am
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Anti-lymphocyte monoclonal antibodies (under construction)
The anti-lymphocyte monoclonal antibodies suppress lymphocyte activity. All such agents must be administered under the supervision of an experienced specialist, in a setting with immediate access to full resuscitation facilities.
efaccena - 12/09/2016 - 1:44pm
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Therapy optimization
Patients with a given disease may differ dramatically in the desired and undesired effects of one and the same standard drug therapy. Extreme examples are:
efaccena - 24/03/2016 - 9:43am