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Antihistamines (under construction)
The antihistamines recommended for or prescribed to treat allergic reactions, occasional insomnia, motion sickness or vertigo, and nausea and vomiting target histamine H1 receptors on mast cells, smooth muscle, endothelium, and in the brain’s tuberomammillary nucleus (a structure of histamine-releasing neurons in the posterior third of the hypothalamus involved in regulating arousal, learning, memory, sleep and energy balance). Antihistamine drugs act mechanistically as receptor antagonists or inverse agonists.
efaccena - 09/09/2016 - 9:21am
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Opioid analgesics
Many opiod analgesics are available to the prescriber.
smaxwell - 10/10/2014 - 7:51pm
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Anti-emetic drugs
Drug-induced emesis can now be largely controlled with anti-emetic drugs, however, nausea remains a very significant clinical problem. This dichotomy suggests that different mechanisms underlie nausea and vomiting.
smaxwell - 10/10/2014 - 7:50pm