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  1. Drug metabolizing enzymes

    Cytochrome P450 enzymes are the main drug metabolising enzymes (xenobiotic inactivators) in humans, and these are the primary contributors to Phase I oxidative metabolism of drugs and other chemicals.

    efaccena - 08/03/2016 - 9:21am

  2. Attention-deficit/-hyperactivity disorder (ADHD)

    Attention-deficit/-hyperactivity disorder (ADHD) is a neurobehavioural and neurodevelopmental syndrome, that is characterised by the onset of persistent hyperactivity, impulsivity, and inattention in children, persisting into adulthood in some cases. The core symptoms are pervasive and become detrimental to home life, psychological, social, and/or educational progress. ADHD might be diagnosed later in life, particularly if hyperactivity is not present. Other mental health conditions may occur along with ADHD, or develop as a result of its effects on quality of life.

    efaccena - 28/02/2023 - 1:52pm

  3. Antidepressant drugs

    In patients with moderate to severe depression routine antidepressant therapy is effective (as highlighted by Cipriani et al. (2018) following meta-analysis of results from clinical trials of 21 different antidepressants)- and is recommended to be combined with psychological therapy. Drug treatment of mild depression may also be considered in patients with a history of moderate or severe depression.

    smaxwell - 10/10/2014 - 7:55pm