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  1. Beta-2 adrenoceptor agonists

    The beta2-adrenoceptor agonist drugs used in respiratory medicine function as long-acting bronchodilators (LABAs). They are prescribed as single agents or in combination with inhaled corticosteroids or muscarinic receptor antagonists.

    smaxwell - 10/10/2014 - 7:39pm

  2. Inhaled corticosteroids

    The inhaled corticosteroids used in respiratory medicine are in fact synthetic agonists of the glucocorticoid receptor (GR), a nuclear hormone receptor in the same family as the androgen, progesterone and mineralocorticoid receptors. GR agonists act to modulate expression of genes containing the glucocorticoid response element (GRE).

    smaxwell - 10/10/2014 - 7:42pm

  3. Corticosteroids

    The anti-inflammatory corticosteroids act as glucocorticoid receptor agonists and modulate expression of genes containing the glucocorticoid response element (GRE).

    efaccena - 09/09/2016 - 9:44am

  4. Chronic obstructive pulmonary disease (COPD)

    COPD is a largely preventable lung condition. The main risk factor for development and exacerbation of COPD is tobacco smoking, but environmental and/or occupational exposure to pollutants is also implicated in the pathology of COPD. A very small number of cases are caused by genetic defects or impaired lung development. Smoking cessation is the most effective way to prevent COPD, or to reduce symptoms and exacerbations from established disease.

    efaccena - 03/03/2023 - 9:36am

  5. Asthma

    Asthma affects 300 million people worldwide and is characterized by respiratory symptoms that burden patients and can lead to exacerbations which require medical attention and can be fatal. Common symptoms of asthma include wheezing, chest tightness, cough and shortness of breath. These symptoms are caused by inflammation and hyperreactivity in the airways leading to bronchoconstriction or airway narrowing. There are many triggers for patients with asthma including dust and allergens, pollution, cigarette smoke and even exercise or stress.

    efaccena - 11/03/2019 - 10:52am