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  1. Antipsychotic drugs

    Antipsychotic use is associated with significant side-effects, most notably movement disorders (tardive dyskinesia) and weight gain. It is unclear whether the atypical (second-generation) antipsychotics offer advantages over older, first generation antipsychotics. Drop-out and symptom relapse rates are similar for both classes of drugs.

    Both generations of medication block receptors in the brain's dopamine pathways, but atypical antipsychotics often act on serotonin receptors as well.

    smaxwell - 10/10/2014 - 7:56pm

  2. Drugs used to manage schizophrenia

    Schizophrenia is a disorder of the mind that is debilitating and chronic. The prevalence of this disorder is about 1% of the population and seems to affect all areas of the globe equally. It is not well understood what causes the disorder.

    efaccena - 20/05/2019 - 1:03pm

  3. 5-HT1 receptor agonists

    The 5-HT1A receptor is a serotonin receptor subtype found in presynaptic and postsynaptic regions of the brain that is implicated in the control of mood, cognition and memory.

    smaxwell - 10/10/2014 - 7:49pm

  4. Schizophrenia

    Schizophrenia is a chronic brain disorder characterised by hallucinations, delusions, formal thought and movement disorders, behavioural changes and a lack of motivation. Symptoms are traditionally divided into positive and negative. The diagnosis is made clinically after a full psychiatric history and other causes of psychosis are excluded. The pathophysiology and causes of schizophrenia are multifaceted and extremely complex and there is no full understanding why it occurs. It has a relatively low prevalence affecting less than 1% of people in their lives.

    efaccena - 05/06/2023 - 9:46am