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Phosphodiesterase inhibitors
Phosphodiesterases (PDEs) are enzymes responsible for the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). There are many subtypes of phosphodiesterases and many inhibitors which can be either non-specific, or selective in their inhibitory profile.
efaccena - 08/03/2016 - 9:19am
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Phosphodiesterase inhibitors and prostaglandins
Phosphodiesterase type 5 (PDE5) inhibitors for erectile dysfunction
efaccena - 05/07/2016 - 2:55pm
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Drug metabolizing enzymes
Cytochrome P450 enzymes are the main drug metabolising enzymes (xenobiotic inactivators) in humans, and these are the primary contributors to Phase I oxidative metabolism of drugs and other chemicals.
efaccena - 08/03/2016 - 9:21am