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1. Drug interactions - Metabolism

   Many drugs rely on metabolism by different isoenzymes of cytochrome P450 (CYP) in the liver, especially 3A, 2D6, 2C9, 2C19, and 1A2. Interacting drugs have the potential to either increase the rate of metabolism by inducing the formation of more CYP isoenzyme or decrease metabolism by inhibiting isoenzyme activity.

   smaxwell - 13/10/2014 - 8:07pm

2. Transporters as drug targets, and drug interactions

   Monoamine reuptake transporters

   efaccena - 21/03/2016 - 1:57pm