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  1. Antimycobacterial drugs

    The most common mycobacterial infections globally are tuberculosis (TB) and leprosy.

    Tuberculosis is a bacterial infection caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs, but can also affect other parts of the body. According to the World Health Organization (WHO), there were an estimated 10 million cases of TB worldwide in 2020, with the highest burden of disease in Asia and Africa.

    efaccena - 11/05/2023 - 2:28pm

  2. Drug interactions - Metabolism

    Many drugs rely on metabolism by different isoenzymes of cytochrome P450 (CYP) in the liver, especially 3A, 2D6, 2C9, 2C19, and 1A2. Interacting drugs have the potential to either increase the rate of metabolism by inducing the formation of more CYP isoenzyme or decrease metabolism by inhibiting isoenzyme activity.

    smaxwell - 13/10/2014 - 8:07pm

  3. Transporters as drug targets, and drug interactions

    Monoamine reuptake transporters

    efaccena - 21/03/2016 - 1:57pm