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Mast-cell stabilisers (under construction)
Mast cell stabilizers are generally cromone derivative type compounds. Mechanistically, they work in part by blocking calcium channels involved in release of preformed chemical mediators such as histamine from intracellular mast cell granules.
efaccena - 12/09/2016 - 10:21am
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Asthma
Asthma affects 300 million people worldwide and is characterized by respiratory symptoms that burden patients and can lead to exacerbations which require medical attention and can be fatal. Common symptoms of asthma include wheezing, chest tightness, cough and shortness of breath. These symptoms are caused by inflammation and hyperreactivity in the airways leading to bronchoconstriction or airway narrowing. There are many triggers for patients with asthma including dust and allergens, pollution, cigarette smoke and even exercise or stress.
efaccena - 11/03/2019 - 10:52am