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  1. Opioid analgesics

    Many opiod analgesics are available to the prescriber.

    smaxwell - 10/10/2014 - 7:51pm

  2. Drug metabolism

    The primary objective of drug metabolism is to facilitate a drug’s excretion by increasing its water solubility (hydrophilicity). The involved chemical modifications incidentally decrease or increase a drug’s pharmacological activity and/or half-life, the most extreme example being the metabolic activation of inactive prodrugs into active drugs, e.g.

    media - 23/05/2014 - 10:25am

  3. Mechanisms of analgesia 2017_2018

    This set of 17 slides introduces students (beginner to intermediate learners) to some of the basic physiological processes that are the targets of many analgesic drug classes. Specific areas covered include the regulation of nociceptive input to the spinal cord by processes within the superficial layers of the cord itself and also descending fibres from the brainstem.

    efaccena - 11/07/2018 - 9:05am

  4. Drug metabolizing enzymes

    Cytochrome P450 enzymes are the main drug metabolising enzymes (xenobiotic inactivators) in humans, and these are the primary contributors to Phase I oxidative metabolism of drugs and other chemicals.

    efaccena - 08/03/2016 - 9:21am

  5. Diarrhoea

    Diarrhoea is the abnormal passing of loose or liquid stools, with increased frequency, increased volume, or both. It can be classified based on its duration into:

    efaccena - 09/02/2023 - 1:44pm