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  1. Antiplatelet drugs

    Antiplatelet drugs are designed to decrease platelet aggregation to inhibit thrombus formation in the arterial circulation. Used to treat patients with cardiac and cerebrovascular conditions.

    They are classified according to their mechanism of action:

    smaxwell - 10/10/2014 - 9:12am

  2. Phosphodiesterase inhibitors

    Phosphodiesterases (PDEs) are enzymes responsible for the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). There are many subtypes of phosphodiesterases and many inhibitors which can be either non-specific, or selective in their inhibitory profile.

    efaccena - 08/03/2016 - 9:19am

  3. Ischemic heart disease

    Oxygen demand of the heart dynamically changes, and the coronary artery can adjust its blood flow to fulfill the myocardial oxygen demand (coronary blood flow reserve). Normally, the oxygen supply and the oxygen demand are well balanced in healthy subjects. When the oxygen supply to the heart becomes inadequate for the needs of the heart, myocardial ischemia occurs. That is, ischemic heart disease (IHD) is caused by an imbalance between the oxygen supply (coronary blood flow) and the oxygen demand of the heart.

    efaccena - 13/02/2018 - 10:14am