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1. Antipsychotic drugs

   Antipsychotic use is associated with significant side-effects, most notably movement disorders (tardive dyskinesia) and weight gain. It is unclear whether the atypical (second-generation) antipsychotics offer advantages over older, first generation antipsychotics. Drop-out and symptom relapse rates are similar for both classes of drugs.

   Both generations of medication block receptors in the brain's dopamine pathways, but atypical antipsychotics often act on serotonin receptors as well.

   smaxwell - 10/10/2014 - 7:56pm

2. Anti-emetic drugs

   Drug-induced emesis can now be largely controlled with anti-emetic drugs, however, nausea remains a very significant clinical problem. This dichotomy suggests that different mechanisms underlie nausea and vomiting.

   smaxwell - 10/10/2014 - 7:50pm

3. Schizophrenia

   Schizophrenia is a disorder of the mind that is debilitating and chronic. The prevalence of this disorder is about 1% of the population and seems to affect all areas of the globe equally. It is not well understood what causes the disorder.

   efaccena - 20/05/2019 - 1:03pm