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  1. Beta-adrenoceptor blocking drugs

    Beta blockers, also known as beta-adrenoceptor blocking agents, are pharmaceutical agents that act as competitive antagonists of the β-adrenoceptors, which are activated by the endogenous catecholamines epinephrine (adrenaline) and norepinephrine (noradrenaline), of the sympathetic nervous system.

    smaxwell - 10/10/2014 - 9:04am

  2. Heart failure

    Heart failure (HF) is caused by the heart’s inability to pump enough blood to meet the body’s needs. In response, the body activates compensatory mechanisms, such as the sympathetic nervous system which leads to tachycardia, sodium and water retention, vasoconstriction, and over time, ventricular hypertrophy, all geared towards increasing cardiac output. Leading causes of HF are coronary artery disease and hypertension.

    efaccena - 11/03/2019 - 11:56am